Sentinel Site Reports

Each month, NDEWS Sentinel Site Directors report on the current landscape of drug use in their communities through quantitative and qualitative data. Trends include data on drug seizures, laboratory testing, community drug checking, novel psychoactive substances, and overdoses (fatal and nonfatal). Continuous integration of these reports ensures NDEWS can issue timely public health alerts and adapt strategies to minimize harms as trends evolve.

Site Director reports are archived below:

2026

Sentinel Site Report, July 2026: Local trends on orphines

  • Published in NDEWS Weekly Briefing Issue 300: August 28, 2026

Sentinel Site Report, June 2026: Local trends with ketamine and NPS ketamine analogs

  • Published in NDEWS Weekly Briefing Issue 295: July 31, 2026

Sentinel Site Report, May 2026: Co-use or co-occurrence of substances in recent trends observed

  • Published in NDEWS Weekly Briefing Issue 290: June 26, 2026

Sentinel Site Report, April 2026: Prevalence and concentration of adulterants in the local drug supply

  • Published in NDEWS Weekly Briefing Issue 286: May 29, 2026

Sentinel Site Report, Q1 2026 in Review: What notable changes or signals in drug supply, overdose indicators, and other substance use trends were observed between January and March 2026?

  • Published in NDEWS Weekly Briefing Issue 280: April 24, 2026

Sentinel Site Report, February 2026: Trends involving carfentanil in the local drug supply?

  • Published in NDEWS Weekly Briefing Issue 276: March 27, 2026

Sentinel Site Report, January 2026: Trends involving nitazenes in the local drug supply?

  • Published in NDEWS Weekly Briefing Issue 272: February 27, 2026

Sentinel Site Report, Year in Review (2025): Full report version – What were distinct trends related to substance use, adulterants, overdoses (nonfatal and/or fatal) observed in 2025 compared to previous year(s)?

  • Many site directors reported on changes in the rates of overdoses and shifts in the local drug supply, including 3 directors mentioning the emergence of medetomidine in 2025.
  • Summary snapshot version of 2025 Year in Review report
    • Published in NDEWS Weekly Briefing Issue 268: January 30, 2026

2025

Sentinel Site Report, October 2025: SSD Report

  • Published in NDEWS Weekly Briefing Issue 262: December 19, 2025

Sentinel Site Report, September 2025: Dissociatives or “club drugs” in the local drug supply

  • Published in NDEWS Weekly Briefing Issue 258: November 21, 2025

Sentinel Site Report, August 2025: Synthetic cathinones or “bath salts” in the local drug supply

  • Published in NDEWS Weekly Briefing Issue 253: October 17, 2025

Sentinel Site Report, July 2025: “Pharmacological” adulterants in the local drug supply

  • Published in NDEWS Weekly Briefing Issue 249: September 19, 2025

Sentinel Site Report, June 2025: Heroin-related trends

  • Published in NDEWS Weekly Briefing Issue 244: August 15, 2025

Sentinel Site Report, May 2025: Carfentanil & fatal and nonfatal overdose-related trend

  • Published in NDEWS Weekly Briefing Issue 240: July 18, 2025

Sentinel Site Report, April 2025: Stimulant Related Trends

  • Published in NDEWS Weekly Briefing Issue 237: June 27, 2025

Sentinel Site Report, March 2025: Notable trends from 2024

  • Published in NDEWS Weekly Briefing Issue 227: April 18, 2025

2024

Notes from Site Directors

Quotes from NDEWS Sentinel Site Directors regarding substance use, overdoses (fatal or nonfatal), or other drug-related trends in their area

NDEWS Sentinel Site Report, April 2024: Insights into pentobarbital

  • Published in NDEWS Weekly Briefing Issue 178: April 19, 2024

NDEWS Sentinel Site Report, February 2024: Trends in recreational ketamine use

  • Published in NDEWS Weekly Briefing Issue 174: March 22, 2024

2023

Rapid Reports

NDEWS Sentinel Site Report, August 2023: What is happening in your area regarding xylazine-related wounds?

NDEWS Sentinel Site Directors report, May 2023: Fentanyl Query – What fentanyl is called?/What fentanyl is sold as?

  • Published in NDEWS Weekly Briefing Issue 135: June 2, 2023

N,N-Dimethylpentylone Web Monitoring Report due to Florida and Atlanta Sentinel Site Reports

Notes from Site Directors

NDEWS Sentinel Site Report, November 2023: What have you heard about 2FDCK (2-Fluorodeschloroketamine) in your area?

  • Published in NDEWS Weekly Briefing Issue 162: December 15, 2023

Quotes from NDEWS Sentinel Site Directors regarding N,N-Dimethylpentylone in their area 

Quotes from NDEWS Sentinel Site Directors regarding nitazene analogs in their area

  • Published in NDEWS Weekly Briefing Issue 118: February 3, 2023

Quotes from NDEWS Sentinel Site Directors regarding xylazine’s impact in their area

Quote from Dr. Devika Bhatia, NDEWS Sentinel Site Director

Ozempic misuse responses from our Sentinel Sites

2022

Rapid Reports

SNOW Dashboard for Sentinel Site Data: Q3 2021 RADARS Fentanyl Poisonings

NDEWS Sub-Studies

Gator WATCH™ and NDEWS Partnership: Wastewater collection from Sentinel Sites

2021

Annual Report

National Drug Early Warning System Summary Report for 2021: Results from Sentinel Site Surveillance

Notes from Site Directors

Dr. Jane Maxwell’s question on fentanyl in methamphetamine and cocaine

Rapid Reports

NDEWs Sentinel Site Trend Report- November 2021

Last modified: 06/29/2026

NDEWS is funded by the National Institute on Drug Abuse to the University of Florida (MPI: Cottler (contact), Co-Is: Goldberger, Nixon, Striley), NYU Langone Health (MPI: Palamar), and Florida Atlantic University (Co-I: Barenholtz).