Eighteen NDEWS sentinel sites will collect and submit indicator data on an ongoing basis to characterize trends in drug use, drug availability, and drug-related consequences in their geographic areas. The NDEWS Coordinating Center will also collect data from national sources and agency partners to supplement local sentinel site data.

Indicators and data sources

Indicators data sources
Drug use Combined effort: Rapid Street Reporting (RSR); Coordinating Center: Virtual HealthStreet, NSDUH
Drug availability Sentinel sites: Drug seizures; Coordinating Center: HIDTA PMP drug seizure data
Drug-related mortality Sentinel sites: Medical Examiner data (cause of death and drug detections); Coordinating Center: ODMAP (fatal)
Drug-related morbidity Sentinel sites: Hospital and emergency department admissions, non-fatal overdoses; Coordinating Center: ODMAP (non-fatal), Poison Control
Treatment demand Sentinel sites: Substance use disorder treatment admissions, naloxone distribution
Drug-related infectious diseases Sentinel sites: HIV, hepatitis C, STIs

The National Drug Early Warning System (NDEWS) is funded by the National Institute on Drug Abuse (U01DA051126) to the University of Florida (PI: Cottler; Co-Is: Goldberger, Nixon, Striley), New York University (Co-I: Palamar), and Florida Atlantic University (Co-I: Barenholtz).