National Drug Early Warning System (NDEWS) Weekly Briefing


Alert from the NDEWS Web Monitoring Team: Online mentions of Cyclazodone

What was found? A growing discussion trend for the drug Cyclazodone has emerged on Reddit in Fall 2021 and early 2022.

To what does Cyclazodone refer? Cyclazodone is a stimulant drug. It is legal and sold as a recreational drug and nootropic supplement.

How is it being discussed? Cyclazodone is discussed as a legal substance that causes mild euphoria. Reddit refers to the drug as having milder effects than Adderall. The drug is commonly misspelled as "Cyclazadone".

Drug Terms: Cyclazodone, Cyclazadone.

Methodological Note: Data was collected and analyzed by the NDEWS Web Monitoring Team, led by Dr. Elan Barenholtz and PhD candidate Paul Morris of the Machine Perception and Cognitive Robotics (MPCR) Lab at Florida Atlantic University. Metrics are based on word counts derived from algorithmic monitoring of ~80 drug-oriented Subreddits. No personally identifiable or post-specific information is incorporated in this monitoring process. For more methodological details, see our recent publication.


Q4 2021 Trend Reports

NPS Discovery published their 2021 Q4 trend reports this week. These trend reports describe the most prevalent NPS in Q4 2021 by class, which include etizolam, n-pyrrolidino etonitazene, eutylone, and MDMB-4en-PINACA. View all four reports here.

Q4 2021 recommended scope for NPS testing in the US

NPS Discovery published their Q4 2021 recommended scope for NPS testing in the US this week, these recommendations are based on current trends, and intelligence from extensive collaborations, partnerships, and initiatives which yield national perspectives. Read the full report here.


UNODC Early Warning Advisory (EWA): New synthetic cannabinoid receptor agonists increase structural diversity

The United Nations Office on Drugs and Crime released a report on the emergence of new synthetic cannabinoid receptor agonists. Since 2009 a total of 320 different synthetic cannabinoid receptor agonists have been reported to the UNODC Early Warning Advisory, with the majority belonging to the structural group of aminoalkylindoles and aminoalkylindazoles. Read the full report here.

Estimating naloxone need in the US across fentanyl, heroin, and prescription opioid epidemics: a modeling study

A study funded by the National Institute on Drug Abuse, and published in Lancet Public Health, examined the state-level naloxone need in the US in 2017.  Read the full study here.

Postdoctoral Fellowships Available Immediately!

The University of Florida Substance Abuse Training Center in Public Health T32 is seeking applicants for two postdoctoral fellowship openings! 

- Fellowships are sponsored by the National Institute on Drug Abuse, and postdocs receive an annual stipend and health benefits for 2 years. 

- An annual allowance is offered to facilitate attendance at conferences.

- Fellows would work on NDEWS, the ABCD study or other NIDA funded studies with internationally known mentors.

- UF resources include: CTSA; McKnight Brain Institute; Center on Addiction Research and Education; Arts in Medicine; Pain Research and Intervention Center of Excellence; UF Health Cancer Center; Emerging Pathogens Institute; Institute on Aging

- The T32 program is directed by Dr. Linda Cottler, and co-directed by Dr. Sara Jo Nixon.

Questions should be directed to Ms. Tamara Millay at Applications are considered on a rolling basis; the program values the diversity of its applicants.

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