National Drug Early Warning System (NDEWS) Weekly Briefing


Alert from the NDEWS Web Monitoring team: Recent growth in online discussions of M30

What was found? A sharp rise in online mentions of “M30” peaked in late September, 2021. A substantial minority (7.96%) of recent Subreddit comments co-mention the terms "M30" and fentanyl (April 2019 - October 2021).

To what does M30 refer? M30 refers to blue, 30mg oxycodone, pills pressed with the M30 imprint. The term can also refer to counterfeit pills containing other substances (such as fentanyl) marketed as oxycodone 30mg.

How is it being discussed? The recent trend of M30 pill discussion coincides with increased mentions of fentanyl. This online finding corroborates real-world observations of an epidemic in counterfeit M30 tablets containing fentanyl.

Drug Terms: Fentanyl, Fentanyl M30, M30, M-30

Methodological Note: Data was collected and analyzed by the NDEWS Web Monitoring Team, led by Dr. Elan Barenholtz and PhD candidate Paul Morris of the Machine Perception and Cognitive Robotics (MPCR) Lab at Florida Atlantic University. Metrics are based on word counts derived from algorithmic monitoring of ~80 drug-oriented Subreddits. No personally identifiable or post-specific information is incorporated in this monitoring process. For more methodological details, see our recent publication."

Word Cloud Note: The Subreddit word cloud presents an aggregate summary of common terms in comments mentioning M30 pills that co-mention fentanyl.


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• Tablets labeled as M30

• Green Machine sold as Fentanyl

New Substances Survey


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NPS Discovery announced three newly identified novel psychoactive substances earlier this week. 5F-BZO-POXID, and BZO-HEXOXIZID (aka MDA 19) were detected in plant-like materials sold as typical synthetic cannabinoid products. View each of their monographs here.


Growing racial/ethnic disparities in overdose mortality before and during the COVID-19 pandemic in California

study recently published in Drug and Alcohol Dependence estimated trends in quarterly overdose mortality in California. Trends were also examined by race/ethnicity and by drug involvement over time. Rates significantly exceeded forecasted trends for all racial/ethnic groups. A 52.4% increase was found for Blacks/African Americans from 2019, compared to 42.6% among Whites counterparts. The absolute Black-White overdose mortality gap rose from 0.7 per 100,000 Black persons in 2018 to 4.8/100,000 in 2019 and further increased to 9.9 during the pandemic. Fatal overdoses among Blacks in California were 34.3% higher than those for Whites in Q2 to 4 of 2020. Read the full study here.


Buprenorphine misuse decreased among adults in America with opioid use disorder from 2015-2019

In a study conducted by the National Institute on Drug Abuse (NIDA), data indicated that in 2019, nearly three-fourths of US adults reporting buprenorphine use did not misuse medication in the past 12 months. In addition, buprenorphine misuse among young people with opioid use disorder trended downward between 2015 and 2019, despite increases in the number of people receiving buprenorphine treatment. Read the full study here.

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